The Orange County Sheriff Coroner's office told the MailOnline that the estimated time of death was Friday at 10am and said he died from a self-inflicted gunshot wound.
The evangelical pastor of Saddleback Church in Lake Forest, California revealed his son's death to his church on Saturday.
'No words can express the anguished grief we feel right now,' the pastor told his congregation in a statement, pleading for their prayers as the family mourned.
Loss: Rick Warren's son Matthew committed suicide on Friday at the age of 27, after a long battle with depression
Family: Kay and Rick Warren have two other adult children, Amy and Joshua. Kay Warren is active in her husband's ministry
Despite countless doctors and medication, 'the torture of mental illness never subsided.'
'Kay and I often marveled at his courage to keep moving in spite of relentless pain. I'll never forget how, many years ago, after another approach had failed to give relief, Matthew said "Dad, I know I¹m going to heaven. Why can't I just die and end this pain?" but he kept going for another decade,' the grieving pastor continued.